Facilitated Variation in the Genome

The discovery of DNA has transformed our view of biology.  Biology is not just organized chemicals - it is information at work.  One of the surprising discoveries in recent times is that cells can facilitate their own evolution.  Mutations can no longer be assumed to be haphazard accidents - many of them are triggered by biological processes in the cell to aid them in generating responses to environmental cues or generating "hedge" mutations in order to help the population survive catastrophe.

The Blyth Institute is actively engaged in the following areas of study within facilitated variation:

  • Developing tests and techniques for distinguishing haphazard mutations from those generated by the cells
  • Determining what sorts of features in the genome require facilitation for them to come into existence
  • Finding the ways in which the genome is organized to better facilitate its own variation
  • Using design patterns in computer science to better understand similar design patterns within the cell

Technical Papers

See our list of technical papers.